Methods for incorporating CATs (including ePROs) into clinical trials and clinical practice – operational and scientific challenges and solutions

Description

In this webinar, we intend to provide an overview of considerations for using CAT and ePROs in clinical trials and clinical practice. We will describe methods for incorporating CAT and ePROs, as well as discuss operational and scientific challenges and their solutions, including a combination of the theory behind CAT and practical examples of incorporating CAT in the real world.

At the conclusion of the webinar, participants will have a deeper understanding of the current state of evidence on the inclusion of CAT and ePROs in clinical trials and clinical practice. They will also gain insights into research gaps and potential operational and scientific challenges for incorporating CAT and ePROs into clinical trials and clinical practice and their solutions.

Background

Computerized adaptive testing (CAT) and ePROs refer to systems and statistical models that allow the assessment of patient-reported outcomes (PROs) electronically. While ePRO refers to electronic data collection of PROs in general, CAT is a dynamic system that adapts PRO assessment to the individual respondent. This individualized assessment has been proven to require fewer items to achieve the same measurement precision as static PRO measures. This happens in real time, such that a response to the first item will help determine which item should be administered next.

Learning Outcomes/Objectives

After the webinar, the learner will be able to:

  • Explain the benefits of incorporating CAT and ePROs into clinical trials and clinical practice
  • Understand the methods for incorporating CAT and ePROs into clinical trials and clinical practice
  • Outline operational and scientific challenges to incorporating CAT and ePROs into clinical trials and clinical practice and their solutions

Presenters

  • Mogens Groenvold, MD, PhD, Professor, University of Copenhagen
  • Matthias Rose, MD, PhD, Professor, Charité – Universitätsmedizin Berlin
  • Amanda Spraggs-Hughes, MA, Associate

Moderator:
Sandra Nolte, PhD, Principal, ICON plc; affiliation: Charité – Universitätsmedizin Berlin

Organized By:
ISOQOL Webinar Committee – A subcommittee of the Education Committee

Cost

Member
$75.00

Nonmember
$100.00

Student
$25.00

Retired
$25.00

Special
$25.00

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