International Society for Quality of Life Research
International Society for Quality of Life Research

Archived Webinars

----------------------------------------------------------------------------------------------------
How to Write a Good Peer Review for an Academic Journal
(May 2017)

Presented By: New Investigator SIG

Background:

Learn the Do's and Don'ts of writing a constructive peer-review.

At the end of the webinar you'll have a better understanding of what is peer-review, why you should engage in peer-review, and what to consider before agreeing to review an article.

Description:

This webinar will focus on the peer review process with a special focus on PROMs and QOL. New and experienced researchers will discuss importance of a sound review and establish a structured approach and criteria to facilitate the peer-review process.

Learning Objectives:

  • Participants will learn important aspects of a reviewing a manuscript for a scientific journal
  • Participants will be able to write a sound and structured peer-review

Presenters

William R. Lenderking, PhD, Vice President, Outcomes Research, Evidera

Jan. R. Boehnke, PhD, Senior Research Fellow in Evaluation Design and Research Methods, Dundee Centre for Health and Related Research
School of Nursing and Health Sciences, University of Dundee

Moderated by: Kathryn Fischer, Charite Universitatsmedizin Berlin

----------------------------------------------------------------------------------------------------
Standardized Evaluations of Patient Reported Outcomes (PRO): the EMPRO Methodology
(July 2016)

Presented By: The Ibero SIG

Background:

Researchers and health professionals face the problem of selecting the most appropriate PRO tool for a given purpose among competing instruments. This webinar will focus on how to support decision making through validated standardized assessment of metric properties and issues related to administration of PROs with the ‘Evaluating Measures of Patient Reported Outcomes’ (EMPRO) system.

Description:

EMPRO was developed to assess an instrument’s quality, considering all available information. It consists of standardized expert evaluations of 8 key measurement attributes for each PRO, resulting in scores that allow direct comparisons among instruments. These attributes were originally proposed by the Medical Outcomes Trust: Concept and measurement model; Reliability; Validity; Sensitivity to change; Interpretation; Burden; Alternative modes of administration, and Cultural adaptation.

The purposes of this webinar are to define each attribute assessed by this tool, and to explain how to apply them to generic and specific PROs. The scoring algorithm and its rationale will be described. Other complementary evaluative tools, such as the COSMIN checklist to appraise the methodological quality of metric properties’ studies, will be addressed. This webinar includes lessons for all researchers interested in valuation of metric properties.

Learning Objectives:

To recognize and apply the criteria required for the evaluation of the eight attributes assessed with EMPRO system: Reliability; Validity; Sensitivity to change; Interpretation; Burden; Alternative modes of administration, and Cultural adaptation.

Presenters

Jordi Alonso, MD PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Montse Ferrer, MD MPH PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Gemma Vilagut, MSc, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Olatz Garin, PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Jose M. Valderas, MD MPH PhD, University of Exeter Medical School, PenCLAHRC, Institute of Health Services Research

Moderated by: Carlos Garcia Forero, PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

----------------------------------------------------------------------------------------------------
Statistical Methods for Response Shift Detection (June 2016)

Presented By: The Response Shift SIG

Description

Response shift (RS) refers to a change in an individual’s perceptions of his/her quality of life (QOL) or health status over time. According to Sprangers and Schwartz (1999), RS can result from three different processes: recalibration (changes in the individual’s internal standards of measurements), reprioritization (changes in the individual’s values and in the relative importance given to the questions or dimensions constituting the target construct), and reconceptualization (changes in the individual’s definition of the target construct). A literature review of RS presented at a previous ISOQOL webinar revealed that RS can occur for many different acute and chronic medical conditions and procedures, including surgeries and stroke. RS can impact the ability to detect change in QOL over time, which could ultimately impact on patient care.

The current webinar will focus specifically on important and cutting-edge statistical methods for RS detection and adjustment for true change estimation, including latent variable modelling and relative importance analysis. Specifically, leading RS researchers will discuss the use of structural equation modelling (SEM), Item Response/Rasch Measurement Theory (IRT/RMT), and importance measures based on logistic regression and discriminant analysis. The strengths, limitations, and assumptions of the methods will be reviewed, as will the types of RS that can be detected with each method. An overview of available software to implement these methods will be provided. Future directions of research in the field will be discussed.

Learning Objectives

  • Participants will learn about different statistical methods that can be used for RS detection and adjustment for true change estimation
  • Participants will be able to critically compare the leading statistical methods for RS analysis and interpretation based on latent variable modelling and relative importance analysis
  • Participants will be able to assess the potential influence that RS has on the assessment of changes in patients’ health status and quality of life over time in longitudinal studies

Presenters

Lisa Lix, Professor & Manitoba Research Chair, BSHEc, MSc, PhD, P.Stat, University of Manitoba

Bellinda King-Kallimanis, Sr Scientist, Psychometrics & Biostatistics, BSc, MSc, PhD, Pharmerit International

Myriam Blanchin, Research Engineer in Biostatistics, BSc, MSc, PhD, EA 4275 SPHERE "methodS in Patient-centered outcomes and HEalth ResEarch", University of Nantes

Moderated by: Véronique Sébille , Professor of Biostatistics, BSc, MSc, PhD, ScD, EA 4275 SPHERE "methodS in Patient-centered outcomes and HEalth ResEarch", University of Nantes

----------------------------------------------------------------------------------------------------
Evaluaciones estandarizadas de Resultados Percibidos por
los Pacientes (PRO): método EMPRO (June 2016)

SPANISH VERSION

Antecedentes:

Los investigadores y profesionales de la salud se enfrentan al problema de seleccionar el instrumento de Resultados Percibidos por los Pacientes (PRO, en inglés) más apropiada para cada ocasión, de entre los diversos instrumentos existentes. Este seminario se centrará en cómo apoyar la toma de decisiones a través de una evaluación estandarizada y validada de las propiedades métricas y las cuestiones relacionadas con la administración de resultados reportados por los pacientes mediante el sistema de “Evaluación de  Medidas de Resultados Percibidos por los Pacientes” (EMPRO).

Descripción:

EMPRO fue desarrollado para evaluar la calidad de un instrumento, teniendo en cuenta toda la información disponible. Se incluyen evaluaciones estandarizadas de expertos de los 8 atributos principales para la medición de cada PRO, dando lugar a puntuaciones que permitan comparaciones directas entre instrumentos. Estos atributos fueron propuestos originalmente por la Medical Outcomes Trust: Modelo conceptual y de medición; Fiabilidad; Validez; Sensibilidad al cambio; Interpretabilidad; Carga de administración; Modos de administración alternativos, y Adaptación cultural.

El propósito de este seminario es definir cada atributo evaluado por esta herramienta, y explicar cómo aplicarlos a los PROs genéricos y específicos. Se describirá el algoritmo de puntuación y su razón de ser. También se abordarán otras herramientas de evaluación complementarias, como la lista de verificación COSMIN para evaluar la calidad metodológica de los estudios de propiedades métricas. Este seminario incluye temas que pueden ser de interés para todos los investigadores que trabajen en la evaluación de las propiedades métricas.

Objetivos De Aprendizaje:

Reconocer y aplicar los criterios necesarios para la evaluación de los ocho atributos evaluados con el sistema EMPRO: Modelo conceptual y de medición; Fiabilidad; Validez; Sensibilidad al cambio; Interpretabilidad; Carga de administración; Modos de administración alternativos, y Adaptación cultural.

Presenters /Presentadores

Jordi Alonso, MD PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Montse Ferrer, MD MPH PhD, Institut Hospital del Mar d'Investigacions Médiques. Health Services Research Group

Gemma Vilagut, MSc, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Carlos Garcia Forero, PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Olatz Garin, PhD, Institut Hospital del Mar d'Investigacions Médiques, Health Services Research Group

Jose M. Valderas, MD MPH PhD, University of Exeter Medical School, PenCLAHRC, Institute of Health Services Research

----------------------------------------------------------------------------------------------------
Response Shift: A Review of the Literature (January 2016)

Response shift (RS) refers to changes in an individual’s self-evaluation of his/her health status and quality of life because of changes in internal standards, values, or concepts. According to Sprangers and Schwartz (1999), there are three types of RS, including (a) recalibration (change in internal
standards of measurements), (b) reprioritization (change in prioritization of component domains constituting the target construct), and (c) reconceptualization (redefinition of the target construct). RS has been investigated in a number of medical conditions where the diagnosis, or treatment, or other factors may act as catalysts that induce change in an individual’s self-perceptions of health status and quality of life. It has been shown that response shift could influence assessments of treatment effects and changes in patients’ health status and quality of life over time.

A number of methods for measuring and detecting response shift have been developed and tested. Our research team conducted a scoping review on the literature on response shift. In this webinar, based on the results of our scoping review, participants will learn about the literature on response shift, the different types of response shift, the different statistical methods for detecting response shift, and future directions of research in the field.

Learning Outcomes/Objectives (What will the learner be able to do after the webinar?):

  • Participants will learn about the results of our scoping review of the response shift literature
  • Participants will be able to explain the potential influence that response shift has on the assessment of treatment effects, as well as assessment of changes in patients’ health status and quality of life over time
  • Participants will be able to critically evaluate and consider the different commonly used statistical methods of response shift
  • Participants will be able to describe the role of response shift in measurement validation (with an emphasis on the modern theories of measurement validity).

Presenters:

Rick Sawatzky, PhD, RN, Associate Professor and Canada Research Chair, School of Nursing, Trinity Western University

Tolu Sajobi, PhD, Assistant Professor, Department of Community Health Sciences, University of Calgary

Ronak Brahmbhatt, MBBS, MPH

----------------------------------------------------------------------------------------------------
Clinical Outcomes Assessment in a Multi-Cultural Context: Measurement Challenges and Recommendations (December 2015)

PRESENTED BY: The Psychometric and Translation & Cultural Adaptation Special Interest Groups

Clinical Outcome Assessment (COA) in an international study requires particular caution due to the differences in language, culture, education, and differing standards of care.  These differences are likely to be sources of variability in measurement outcomes. If not adequately managed, this variability can potentially jeopardize the accurate capture of the targeted concepts, and make the demonstration of treatment benefit more difficult. Cross-cultural equivalence of COAs used in international studies is, therefore, of particular importance. The webinar will present the challenges and discuss possible solutions related to this question.

A certain amount of cross-cultural variation can be prevented using qualitative methods during the development and translation of a COA.  Content can be considered from a cross-cultural perspective using multi-cultural patient interviews and techniques such as Translatability Assessment. Evaluation of cross-cultural equivalence of a measure has traditionally been accomplished using quantitative methods. These methods include investigation of differential item functioning and measurement invariance. Once data have been collected and evaluated quantitatively, further investigation can be conducted qualitatively to focus on specific areas of variability that raise questions about equivalency or comparability. Once the cross-cultural equivalence of a COA used in a multicultural study has been tested and variability addressed using both qualitative and quantitative methods, a more clear demonstration of a treatment benefit can be ascertained with confidence in the results.

These topics and methods for early qualitative and quantitative evaluation will be described, using examples, during the webinar by speakers from both the Translation and Cultural Adaptation and Psychometrics Special Interest Groups of ISOQOL. The presentation will be followed by an interactive Q&A session during which the speakers will address questions from the audience.

Learning Outcomes/Objectives (What will the learner be able to do after the webinar?):

  • To anticipate potential measurement issues related to cultural differences in the context of a multi-cultural study
  • To outline a strategy to investigate cross-cultural equivalence of COAs using appropriate quantitative and qualitative methods

Presenters:

Stacie Hudgens, MA (AbD) Managing Partner, Strategic Lead for Clinical Outcome Solutions

Antoine Regnault, PhD Research Director for Mapi

Lori McLeod, PhD Head, Psychometrics for RTI Health Solutions

Mona Martin, RN MPA Executive Director for Health Research Associates Inc.

Sonya Eremenco, MA Director, ePRO New Products for Evidera, Inc.

Sponsored by:

Sponsored by:

----------------------------------------------------------------------------------------------------
Applying the FDA Patient-reported Outcome (PRO) Guidance to Performance Outcome (PerfO) Measures
(November 2015)

PRESENTED BY: The Industry Special Interest Group (Formerly the Industry Advisory Committee - IAC)

The FDA PRO Guidance of 2009 provides a gold standard against which the appropriateness of PRO measures for use in clinical trials are assessed. The principles that apply to PROs broadly apply to other types of assessments such as PerfOs. This session provides examples of PerfOs, including cognitive and physical functioning assessments and highlights the importance of establishing conceptual relevance and ecological validity. Included is an overview of innovative technologies such as preference-based studies, cognitive task analysis and video diaries.

Learning Objectives are:

  • Understand the importance of conceptual relevance and ecological validity of PerfOs
  • Learn how innovative methods (e.g. cognitive task analysis) provide insights into decision making when administering and completing these tasks

Presenters:

Fiona McDougall, PhD ClinPsyD, Roche Products Limited

Louise Humphrey, MSc

Lee Scott Ehrhart, PhD,
MITRE Corporation

Helen A. Doll, MSc DPhil, ICON Patient Reported Outcomes

Moderated by: Diana Rofail, CPsychol, Roche Products Limited

Sponsored by:

----------------------------------------------------------------------------------------------------
Doc, how bad is it? Setting standards for severity of patient reported outcomes data using item banks from PROMS and Neuro-QOL
(June 2015)

The goal of the workshop is to teach health outcomes researchers how to develop and conduct a standard-setting protocol in order to identify cut scores for clinical levels of PRO domains.

Learning Objectives are:

  • Participants will be able to identify at least three benefits of having clinical classification systems for PRO scores.
  • Participants will identify methods for validating cut-scores based on empirical data.
  • Participants will be able to identify areas for future research on the generalizability of Bookmarking results.

Presenters:

Karon F. Cook, PhD, Research Professor, Feinberg School of Medicine, Northwestern University

Deborah M. Miller, PhD, Associate Professor, Mellen Center, Cleveland Clinic

David E. Victorson, PhD, Associate Professor Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University

----------------------------------------------------------------------------------------------------
Group Concept Mapping: A patient-centric, mixed-methods, approach to understand the patients' experiences and support outcomes strategy
(January 2015)

The audience will benefit and get an understanding of the history and application of mixed methods approaches to outcomes research and learn how to apply an innovative, mixed methods approach with a strong patient-centric focus, to answer different outcomes research questions.

Learning Objectives are:

  • Understand a brief history of mixed methods research
  • Understand a brief history of Group Concept Mapping approach
  • Understand the 4 steps involved in Group Concept Mapping and how the methodology can be applied to different research questions

Presenters:

Louise Humphrey, MSc, Director of Clinical Outcomes Assessment, Abacus International, UK

Thomas Willgoss, PhD, Project Manager, Abacus International, UK

Tara Symonds, PhD, Partner and Strategic Lead, Clinical Outcomes Solutions, UK

Joseph C Cappelleri, PhD, Senior Director - Biostatistics , Pfizer Inc., US

Moderated by: Josephine M. Norquist, MS, ISOQOL Industry Advisory Committee (IAC) Chair

Sponsored by:

----------------------------------------------------------------------------------------------------
Lessons Learned from the EQ-5D-3L Valuation in Brazil: Presented by Health Preference Research (HPR) SIG & Ibero America SIG
(December 2014)

The purpose of this webinar is to share the Brazilian experience on health preference measurement, through methods and results discussion. In this session the panel of speakers will describe the study design, exploring the alternative methodological options and discussing its impact on value estimation and to states selection. This webinar includes lessons for all researchers interested in valuation studies in developing countries as well as methodological issues with traditional valuation tasks (e.g., TTO).

Presenters:

Marisa Santos, MD, PhD, Instituto Nacional de Cardiologia, Brazil

Monica Akissue Cintra, MD, PhD, Instituto Nacional de Cardiologia, Brazil

Andréa Libório, MSc, Instituto Nacional de Cardiologia, Brazil

Claudia Pereira, PhD, ENSP- FIOCRUZ, Brazil

Marcelo Correa, MSc, Instituto Nacional de Cardiologia, Brazil

----------------------------------------------------------------------------------------------------
Webinar Offerings from the NCI in Collaboration with ISOQOL
(August/September 2014)

Two free educational offerings for researchers are now available from the NCI in collaboration with the International Society for Quality of Life Research.

The first is a new webinar series, Best Practices for Integrating Patient-Reported Outcomes in Oncology Clinical Trials. The series includes 6 videos which can be viewed independently, or in sequence to meet an individual's learning needs. Experts in PRO research present on topics including: selecting PRO measures, designing high quality studies with PRO endpoints, statistical considerations, ensuring data quality, and reporting outcomes.

Another webinar just released, Symptom Management & Quality of Life Concept Design, covers a variety of practical considerations for developing a symptom management concept for clinical research. Experts in the field present on topics including: required elements, statistics, and the community physician perspective.

Both are now live and can be viewed on demand through the NCI Division of Cancer Prevention Website http://prevention.cancer.gov/news-events/events/videos/pro_symptommanagementwebinars.

----------------------------------------------------------------------------------------------------
Lessons Learned from PROs in FDA and EMA Label Claims
(May 2013)

This webinar includes presentations from industry sponsors that have interacted with the FDA or EMA to support labeling of their products. The webinar includes a review of PRO measures and determination of how to move them forward and/or revise them as appropriate to support labeling claims. Specifically, the webinar addresses how to conduct a gap analysis and how to adapt or modify existing measures to assess and/or confirm the validity of the measure. FDA and EMA considerations of PRO measures are addressed through the use of case studies.

Presenters:

Kathy Beusterien, MPH, Senior Director, Oxford Outcomes

Thomas Hare, Vice President, Development Operations, Incyte

William Lenderking, PhD, Senior Research Leader, United BioSource

Linda Abetz-Webb, EU Practice Lead, PRO Adelphi Values

Sponsored by:

----------------------------------------------------------------------------------------------------
Incorporating Patient-Reported Outcomes into Comparative Effectiveness Research
(December 2012)

----------------------------------------------------------------------------------------------------
Using Patient-Reported Outcome Measures to Improve Clinical Practice  
(November 2012)

INTERNATIONAL SOCIETY FOR QUALITY OF LIFE RESEARCH
555 East Wells Street, Suite 1100, Milwaukee, WI USA 53202
Phone: +1 (414) 918-9797; Fax: +1 (414) 276-3349
Email: info@isoqol.org

Facebook Twitter LinkedIn

DISCLAIMER
Throughout the website, ISOQOL provides outside resources that may provide assistance to people interested in health-related quality of life and its assessment. It is recommended that readers conduct their own evaluation of the information outside of ISOQOL activities.

TERMS OF USE  |  PRIVACY POLICY

Home  |  About ISOQOL  |  Membership  |  Research & Publications  |  Education & Events  |  Special Interest Groups  |  Job Board  |  Site Map
© Copyright 2017 International Society for Quality of Life Research. All rights Reserved.